I ordered a pair of 54mm cone filters off of ebay about $20 a pair. They drop right in after ripping out the Rebel's airbox and recycle exhaust thingy.
After doing that - it ran WAY TOO LEAN. It was awful, gasping for gasoline - gasp gasp. . .
My previous experience with bikes told me to get some larger main jets. It turns out the Rebel 450 uses the same jets from my Lifan 200 (a chinese Honda knockoff). They are type Keihin 99101-393.
I ordered 125, 130, and 135 jets - they are about $3 a pair (shipping was more than all 6 jets). My thought was to put in the 130 and then switch up or down depending on what the results were.
I also got some washers to shim up the needle. I expected the pilot screws to be locked in place as all Hondas are - but to my surprise, they were not which leads me to believe that the previous owner already messed with them and installed new pilot screws.
I also found out that the exhaust has been drilled through the first baffle.
Anyways, to make a long story not so long, the 130 jets made things improve but was still a little too lean - especially at 6th gear.
I switched to 135 jets and there it was - 6th gear at 5000 rpm is 75 mph cruising on the highway.
Just as I experienced on my previous bike, the Honda airbox was mondo restrictive - it was not letting the engine rev above 6500rpm. The cone/pod filters removed this restriction and let the engine really let loose.
It turns out that the way it was set up wasn't allowing the bike to use its powerband of 6-8000rpm.
Now it can breath and it really cooks!